HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML

BACKGROUND: Leukaemia stem cells (LSCs) are responsible for the initiation, maintenance, and recurrence of acute myeloid leukaemia (AML), an aggressive haematological malignancy associated with drug resistance and relapse. Identifying therapeutic LSC targets is critical to curing AML. METHODS: Bioin...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Li, Zheng, Wang, Fangce, Tian, Xiaoxue, Long, Jun, Ling, Bin, Zhang, Wenjun, Xu, Jun, Liang, Aibin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223385/
https://ncbi.nlm.nih.gov/pubmed/34167558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02007-4
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