HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML

BACKGROUND: Leukaemia stem cells (LSCs) are responsible for the initiation, maintenance, and recurrence of acute myeloid leukaemia (AML), an aggressive haematological malignancy associated with drug resistance and relapse. Identifying therapeutic LSC targets is critical to curing AML. METHODS: Bioin...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Li, Zheng, Wang, Fangce, Tian, Xiaoxue, Long, Jun, Ling, Bin, Zhang, Wenjun, Xu, Jun, Liang, Aibin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223385/
https://ncbi.nlm.nih.gov/pubmed/34167558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02007-4
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