Protein Phosphatase 4 Promotes Hepatocyte Lipoapoptosis by Regulating RAC1/MLK3/JNK Pathway

Lipotoxicity-induced apoptosis, also referred to as lipoapoptosis, is one of the important initial factors promoting the progression from hepatosteatosis to nonalcoholic steatohepatitis (NASH). Saturated free fatty acids (SFAs), which are increased significantly in NASH, are directly hepatotoxic whi...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Huang, Xiuqing, Yang, Guang, Zhao, Li, Yuan, Huiping, Chen, Hao, Shen, Tao, Tang, Weiqing, Man, Yong, Ma, Jiarui, Ma, Yanyan, Dou, Lin, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221892/
https://ncbi.nlm.nih.gov/pubmed/34221233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5550498
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