Protein Phosphatase 4 Promotes Hepatocyte Lipoapoptosis by Regulating RAC1/MLK3/JNK Pathway

Lipotoxicity-induced apoptosis, also referred to as lipoapoptosis, is one of the important initial factors promoting the progression from hepatosteatosis to nonalcoholic steatohepatitis (NASH). Saturated free fatty acids (SFAs), which are increased significantly in NASH, are directly hepatotoxic whi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Huang, Xiuqing, Yang, Guang, Zhao, Li, Yuan, Huiping, Chen, Hao, Shen, Tao, Tang, Weiqing, Man, Yong, Ma, Jiarui, Ma, Yanyan, Dou, Lin, Li, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221892/
https://ncbi.nlm.nih.gov/pubmed/34221233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5550498
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky