Protein Phosphatase 4 Promotes Hepatocyte Lipoapoptosis by Regulating RAC1/MLK3/JNK Pathway

Lipotoxicity-induced apoptosis, also referred to as lipoapoptosis, is one of the important initial factors promoting the progression from hepatosteatosis to nonalcoholic steatohepatitis (NASH). Saturated free fatty acids (SFAs), which are increased significantly in NASH, are directly hepatotoxic whi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Huang, Xiuqing, Yang, Guang, Zhao, Li, Yuan, Huiping, Chen, Hao, Shen, Tao, Tang, Weiqing, Man, Yong, Ma, Jiarui, Ma, Yanyan, Dou, Lin, Li, Jian
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221892/
https://ncbi.nlm.nih.gov/pubmed/34221233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5550498
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