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Methods to Predict Volume of Distribution

PURPOSE OF REVIEW: Prior to human studies, knowledge of drug disposition in the body is useful to inform decisions on drug safety and efficacy, first in human dosing, and dosing regimen design. It is therefore of interest to develop predictive models for primary pharmacokinetic parameters, clearance...

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Detalhes bibliográficos
Publicado no:Curr Pharmacol Rep
Main Authors: Holt, Kimberly, Nagar, Swati, Korzekwa, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221585/
https://ncbi.nlm.nih.gov/pubmed/34168949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40495-019-00186-5
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