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Large-scale tethered function assays identify factors that regulate mRNA stability and translation
The molecular functions of the majority of RNA-binding proteins (RBPs) remain unclear, highlighting a major bottleneck to a full understanding of gene expression regulation. Here, we develop a plasmid resource of 690 human RBPs that we subject to luciferase-based 3′-untranslated-region tethered func...
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| 出版年: | Nat Struct Mol Biol |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8221285/ https://ncbi.nlm.nih.gov/pubmed/32807991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0477-6 |
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