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Protein-oligonucleotide conjugates as model substrates for DNA-protein crosslink repair proteases
Covalent DNA-protein crosslinks (DPCs) have emerged as pervasive sources of genome instability. DPCs are targeted for repair by DNA-dependent proteases of the Wss1/SPRTN family. However, understanding how these enzymes achieve specificity has been hampered by the lack of suitable in vitro model subs...
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| Publicado no: | STAR Protoc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8219891/ https://ncbi.nlm.nih.gov/pubmed/34189469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100591 |
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