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Post-symptomatic Delivery of Brain Derived Neurotrophic Factor (BDNF) Ameliorates Spinocerebellar Ataxia Type 1 (SCA1) Pathogenesis
Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by an abnormal expansion of CAG repeats in the Ataxin1 (ATXN1) gene. SCA1 is characterized by motor deficits, cerebellar neurodegeneration, gliosis and gene expression changes. Expression of brain derived neurotrophic f...
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| Veröffentlicht in: | Cerebellum |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8217121/ https://ncbi.nlm.nih.gov/pubmed/33394333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-020-01226-3 |
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