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Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates

A primary goal of HIV-1 vaccine development is the consistent elicitation of protective, neutralizing antibodies. While highly similar neutralizing antibodies (nAbs) have been isolated from multiple HIV-infected individuals, it is unclear whether vaccination can consistently elicit highly similar nA...

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Vydáno v:PLoS Pathog
Hlavní autoři: Cai, Fangping, Chen, Wei-Hung, Wu, Weimin, Jones, Julia A., Choe, Misook, Gohain, Neelakshi, Shen, Xiaoying, LaBranche, Celia, Eaton, Amanda, Sutherland, Laura, Lee, Esther M., Hernandez, Giovanna E., Wu, Nelson R., Scearce, Richard, Seaman, Michael S., Moody, M. Anthony, Santra, Sampa, Wiehe, Kevin, Tomaras, Georgia D., Wagh, Kshitij, Korber, Bette, Bonsignori, Mattia, Montefiori, David C., Haynes, Barton F., de Val, Natalia, Joyce, M. Gordon, Saunders, Kevin O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216552/
https://ncbi.nlm.nih.gov/pubmed/34086838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009624
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