DeepCleave: a deep learning predictor for caspase and matrix metalloprotease substrates and cleavage sites

MOTIVATION: Proteases are enzymes that cleave target substrate proteins by catalyzing the hydrolysis of peptide bonds between specific amino acids. While the functional proteolysis regulated by proteases plays a central role in the ‘life and death’ cellular processes, many of the corresponding subst...

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Li, Fuyi, Chen, Jinxiang, Leier, André, Marquez-Lago, Tatiana, Liu, Quanzhong, Wang, Yanze, Revote, Jerico, Smith, A Ian, Akutsu, Tatsuya, Webb, Geoffrey I, Kurgan, Lukasz, Song, Jiangning
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Original Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215920/
https://ncbi.nlm.nih.gov/pubmed/31566664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz721
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