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Knowledge-transfer learning for prediction of matrix metalloprotease substrate-cleavage sites

Matrix Metalloproteases (MMPs) are an important family of proteases that play crucial roles in key cellular and disease processes. Therefore, MMPs constitute important targets for drug design, development and delivery. Advanced proteomic technologies have identified type-specific target substrates;...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Wang, Yanan, Song, Jiangning, Marquez-Lago, Tatiana T., Leier, André, Li, Chen, Lithgow, Trevor, Webb, Geoffrey I., Shen, Hong-Bin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515926/
https://ncbi.nlm.nih.gov/pubmed/28720874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06219-7
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