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Knowledge-transfer learning for prediction of matrix metalloprotease substrate-cleavage sites

Matrix Metalloproteases (MMPs) are an important family of proteases that play crucial roles in key cellular and disease processes. Therefore, MMPs constitute important targets for drug design, development and delivery. Advanced proteomic technologies have identified type-specific target substrates;...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Yanan, Song, Jiangning, Marquez-Lago, Tatiana T., Leier, André, Li, Chen, Lithgow, Trevor, Webb, Geoffrey I., Shen, Hong-Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515926/
https://ncbi.nlm.nih.gov/pubmed/28720874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06219-7
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