PROSPERous: high-throughput prediction of substrate cleavage sites for 90 proteases with improved accuracy

SUMMARY: Proteases are enzymes that specifically cleave the peptide backbone of their target proteins. As an important type of irreversible post-translational modification, protein cleavage underlies many key physiological processes. When dysregulated, proteases’ actions are associated with numerous...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Song, Jiangning, Li, Fuyi, Leier, André, Marquez-Lago, Tatiana T, Akutsu, Tatsuya, Haffari, Gholamreza, Chou, Kuo-Chen, Webb, Geoffrey I, Pike, Robert N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Applications Notes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860617/
https://ncbi.nlm.nih.gov/pubmed/29069280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx670
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