DeepBL: a deep learning-based approach for in silico discovery of beta-lactamases

Beta-lactamases (BLs) are enzymes localized in the periplasmic space of bacterial pathogens, where they confer resistance to beta-lactam antibiotics. Experimental identification of BLs is costly yet crucial to understand beta-lactam resistance mechanisms. To address this issue, we present DeepBL, a...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Wang, Yanan, Li, Fuyi, Bharathwaj, Manasa, Rosas, Natalia C, Leier, André, Akutsu, Tatsuya, Webb, Geoffrey I, Marquez-Lago, Tatiana T, Li, Jian, Lithgow, Trevor, Song, Jiangning
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Problem Solving Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294541/
https://ncbi.nlm.nih.gov/pubmed/33212503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbaa301
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