Structural insights into the human D1 and D2 dopamine receptor signaling complexes

The D1- and D2-dopamine receptors (D1R and D2R), which signal through G(s) and G(i), respectively, represent the principal stimulatory and inhibitory dopamine receptors in the central nervous system. D1R and D2R also represent the main therapeutic targets for Parkinson’s disease, schizophrenia, and...

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Publicado no:Cell
Main Authors: Zhuang, Youwen, Xu, Peiyu, Mao, Chunyou, Wang, Lei, Krumm, Brian, Zhou, X. Edward, Huang, Sijie, Liu, Heng, Cheng, Xi, Huang, Xi-Ping, Shen, Dan-Dan, Xu, Tinghai, Liu, Yong-Feng, Wang, Yue, Guo, Jia, Jiang, Yi, Jiang, Hualiang, Melcher, Karsten, Roth, Bryan L., Zhang, Yan, Zhang, Cheng, Xu, H. Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215686/
https://ncbi.nlm.nih.gov/pubmed/33571431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.01.027
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