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Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors

Autism spectrum disorder (ASD) is a neurodevelopmental disease associated with various gene mutations. Recent genetic and clinical studies report that mutations of the epigenetic gene ASH1L are highly associated with human ASD and intellectual disability (ID). However, the causality and underlying m...

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Détails bibliographiques
Publié dans:Commun Biol
Auteurs principaux: Gao, Yuen, Duque-Wilckens, Natalia, Aljazi, Mohammad B., Wu, Yan, Moeser, Adam J., Mias, George I., Robison, Alfred J., He, Jin
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213741/
https://ncbi.nlm.nih.gov/pubmed/34145365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02282-z
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