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Novel role of ASH1L histone methyltransferase in anaplastic thyroid carcinoma

Anaplastic thyroid cancer (ATC) is one of the most aggressive human malignancies, with an average life expectancy of ∼6 months from the time of diagnosis. The genetic and epigenetic changes that underlie this malignancy are incompletely understood. We found that ASH1-like histone lysine methyltransf...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Xu, Bin, Qin, Tingting, Yu, Jingcheng, Giordano, Thomas J., Sartor, Maureen A., Koenig, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324504/
https://ncbi.nlm.nih.gov/pubmed/32398261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013530
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