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Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors

Autism spectrum disorder (ASD) is a neurodevelopmental disease associated with various gene mutations. Recent genetic and clinical studies report that mutations of the epigenetic gene ASH1L are highly associated with human ASD and intellectual disability (ID). However, the causality and underlying m...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Gao, Yuen, Duque-Wilckens, Natalia, Aljazi, Mohammad B., Wu, Yan, Moeser, Adam J., Mias, George I., Robison, Alfred J., He, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213741/
https://ncbi.nlm.nih.gov/pubmed/34145365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02282-z
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