Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study

A lubricating microbicide gel designed for rectal and vaginal use would provide a behaviorally congruent strategy to enhance pre-exposure prophylaxis adherence and reduce HIV infection risk. In this study, we report the first-in-human evaluation of such a gel containing 1% IQP-0528, an investigation...

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Dettagli Bibliografici
Pubblicato in:AIDS Res Hum Retroviruses
Autori principali: Al-Khouja, Amer, Shieh, Eugenie, Fuchs, Edward J., Marzinke, Mark A., Bakshi, Rahul P., Hummert, Pamela, Ham, Anthony S., Buckheit, Karen W., Breakey, Jennifer, Weld, Ethel D., Chen, Huan, Caffo, Brian S., Buckheit, Robert W., Hendrix, Craig W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2021
Soggetti:
Clinical Trials/Clinical Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213010/
https://ncbi.nlm.nih.gov/pubmed/33371779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2020.0188
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