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Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study

A lubricating microbicide gel designed for rectal and vaginal use would provide a behaviorally congruent strategy to enhance pre-exposure prophylaxis adherence and reduce HIV infection risk. In this study, we report the first-in-human evaluation of such a gel containing 1% IQP-0528, an investigation...

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Bibliografische gegevens
Gepubliceerd in:AIDS Res Hum Retroviruses
Hoofdauteurs: Al-Khouja, Amer, Shieh, Eugenie, Fuchs, Edward J., Marzinke, Mark A., Bakshi, Rahul P., Hummert, Pamela, Ham, Anthony S., Buckheit, Karen W., Breakey, Jennifer, Weld, Ethel D., Chen, Huan, Caffo, Brian S., Buckheit, Robert W., Hendrix, Craig W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc., publishers 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213010/
https://ncbi.nlm.nih.gov/pubmed/33371779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2020.0188
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