Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study

A lubricating microbicide gel designed for rectal and vaginal use would provide a behaviorally congruent strategy to enhance pre-exposure prophylaxis adherence and reduce HIV infection risk. In this study, we report the first-in-human evaluation of such a gel containing 1% IQP-0528, an investigation...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Al-Khouja, Amer, Shieh, Eugenie, Fuchs, Edward J., Marzinke, Mark A., Bakshi, Rahul P., Hummert, Pamela, Ham, Anthony S., Buckheit, Karen W., Breakey, Jennifer, Weld, Ethel D., Chen, Huan, Caffo, Brian S., Buckheit, Robert W., Hendrix, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2021
Assuntos:
Clinical Trials/Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213010/
https://ncbi.nlm.nih.gov/pubmed/33371779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2020.0188
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