Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study

A lubricating microbicide gel designed for rectal and vaginal use would provide a behaviorally congruent strategy to enhance pre-exposure prophylaxis adherence and reduce HIV infection risk. In this study, we report the first-in-human evaluation of such a gel containing 1% IQP-0528, an investigation...

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Dades bibliogràfiques
Publicat a:AIDS Res Hum Retroviruses
Autors principals: Al-Khouja, Amer, Shieh, Eugenie, Fuchs, Edward J., Marzinke, Mark A., Bakshi, Rahul P., Hummert, Pamela, Ham, Anthony S., Buckheit, Karen W., Breakey, Jennifer, Weld, Ethel D., Chen, Huan, Caffo, Brian S., Buckheit, Robert W., Hendrix, Craig W.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc., publishers 2021
Matèries:
Clinical Trials/Clinical Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213010/
https://ncbi.nlm.nih.gov/pubmed/33371779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2020.0188
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