Safety and Efficacy of tenofovir / IQP-0528 combination gels – a dual compartment microbicide for HIV-1 prevention

Tenofovir (TFV) is a nucleotide reverse transcriptase inhibitor and IQP-0528 is a nonnucleoside reverse transcriptase inhibitor that also blocks virus entry. TFV and IQP-0528 alone have shown antiviral activity as microbicide gels. Because combination therapy will likely be more potent than mono-the...

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Detalhes bibliográficos
Main Authors: Dezzutti, Charlene S., Shetler, Cory, Mahalingam, Alamelu, Ugaonkar, Shweta R., Gwozdz, Garry, Buckheit, Karen W., Buckheit, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501576/
https://ncbi.nlm.nih.gov/pubmed/22940075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.08.004
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