Reformulated tenofovir gel for use as a dual compartment microbicide

OBJECTIVES: Coital use of 1% tenofovir gel was shown to be modestly effective at preventing HIV transmission when applied vaginally in the CAPRISA 004 trial. Because the gel is hyperosmolar, which would reduce the integrity of the epithelium and induce fluid movement into the lumen, rectal use may n...

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Detaylı Bibliyografya
Asıl Yazarlar: Dezzutti, Charlene S., Rohan, Lisa C., Wang, Lin, Uranker, Kevin, Shetler, Cory, Cost, Marilyn, Lynam, J. D., Friend, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417689/
https://ncbi.nlm.nih.gov/pubmed/22581908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks173
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