In Vitro and Ex Vivo Testing of Tenofovir Shows It Is Effective As an HIV-1 Microbicide

BACKGROUND: Tenofovir gel has entered into clinical trials for use as a topical microbicide to prevent HIV-1 infection but has no published data regarding pre-clinical testing using in vitro and ex vivo models. To validate our findings with on-going clinical trial results, we evaluated topical tenof...

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Bibliografische gegevens
Hoofdauteurs: Rohan, Lisa C., Moncla, Bernard J., Kunjara Na Ayudhya, Ratiya Pamela, Cost, Marilyn, Huang, Yunda, Gai, Fang, Billitto, Nicole, Lynam, J. D., Pryke, Kara, Graebing, Phillip, Hopkins, Nicole, Rooney, James F., Friend, David, Dezzutti, Charlene S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824823/
https://ncbi.nlm.nih.gov/pubmed/20174579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009310
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