In Vitro and Ex Vivo Testing of Tenofovir Shows It Is Effective As an HIV-1 Microbicide

BACKGROUND: Tenofovir gel has entered into clinical trials for use as a topical microbicide to prevent HIV-1 infection but has no published data regarding pre-clinical testing using in vitro and ex vivo models. To validate our findings with on-going clinical trial results, we evaluated topical tenof...

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Détails bibliographiques
Auteurs principaux: Rohan, Lisa C., Moncla, Bernard J., Kunjara Na Ayudhya, Ratiya Pamela, Cost, Marilyn, Huang, Yunda, Gai, Fang, Billitto, Nicole, Lynam, J. D., Pryke, Kara, Graebing, Phillip, Hopkins, Nicole, Rooney, James F., Friend, David, Dezzutti, Charlene S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824823/
https://ncbi.nlm.nih.gov/pubmed/20174579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009310
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