Elimination of Age-Associated Hepatic Steatosis and Correction of Aging Phenotype by Inhibition of cdk4-C/EBPα-p300 Axis

The aging liver is affected by several disorders, including steatosis, that can lead to a decline of liver functions. Here, we present evidence that the cdk4-C/EBPα-p300 axis is a critical regulator of age-associated disorders, including steatosis. We found that patients with non-alcoholic fatty liv...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Nguyen, Phuong, Valanejad, Leila, Cast, Ashley, Wright, Mary, Garcia, Jose M., El-Serag, Hashem B., Karns, Rebekah, Timchenko, Nikolai A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209958/
https://ncbi.nlm.nih.gov/pubmed/30089269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.014
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