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Ghrelin deletion protects against age‐associated hepatic steatosis by downregulating the C/EBPα‐p300/DGAT1 pathway

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. NAFLD usually begins as low‐grade hepatic steatosis which further progresses in an age‐dependent manner to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma in some patients. Ghr...

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Publicado en:Aging Cell
Autores principales: Guillory, Bobby, Jawanmardi, Nicole, Iakova, Polina, Anderson, Barbara, Zang, Pu, Timchenko, Nikolai A., Garcia, Jose M.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771394/
https://ncbi.nlm.nih.gov/pubmed/29024407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12688
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