Increased expression of enzymes of triglyceride synthesis is essential for the development of hepatic steatosis

Molecular mechanisms underpinning nonalcoholic fatty liver disease (NAFLD) are not well understood. The earliest step of NAFLD is hepatic steatosis, which is one of the main characteristics of aging liver. Here we present a molecular scenario of age-related liver steatosis. We show that C/EBPα-S193D...

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Main Authors: Jin, Jingling, Iakova, Polina, Breaux, Meghan, Sullivan, Emily, Jawanmardi, Nicole, Chen, Dahu, Jiang, Yanjun, Medrano, Estela M., Timchenko, Nikolai A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615099/
https://ncbi.nlm.nih.gov/pubmed/23499441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.02.009
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