Transcriptional and Translational Regulation of C/EBPβ-HDAC1 Protein Complexes Controls Different Levels of p53, SIRT1, and PGC1α Proteins at the Early and Late Stages of Liver Cancer

Cancer changes biological processes in the liver by altering gene expression at the levels of transcription, translation, and protein modification. The RNA binding protein CUGBP1 is a key regulator of translation of CCAAT enhancer binding protein β and histone deacetylase 1 (HDAC1). These proteins f...

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Autori principali: Jin, Jingling, Iakova, Polina, Jiang, Yanjun, Lewis, Kyle, Sullivan, Emily, Jawanmardi, Nicole, Donehower, Lawrence, Timchenko, Lubov, Timchenko, Nikolai A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656300/
https://ncbi.nlm.nih.gov/pubmed/23564453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460840
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