Ghrelin deletion protects against age‐associated hepatic steatosis by downregulating the C/EBPα‐p300/DGAT1 pathway

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. NAFLD usually begins as low‐grade hepatic steatosis which further progresses in an age‐dependent manner to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma in some patients. Ghr...

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Veröffentlicht in:Aging Cell
Hauptverfasser: Guillory, Bobby, Jawanmardi, Nicole, Iakova, Polina, Anderson, Barbara, Zang, Pu, Timchenko, Nikolai A., Garcia, Jose M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771394/
https://ncbi.nlm.nih.gov/pubmed/29024407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12688
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