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PARP1 activation increases expression of modified tumor suppressors and pathways underlying development of aggressive hepatoblastoma
Hepatoblastoma (HBL) is a pediatric liver cancer that affects children under the age of three. Reduction of tumor suppressor proteins (TSPs) is commonly seen in liver cancer. However, in our studies we find that aggressive, chemo-resistant HBLs exhibit an elevation of TSPs. HBL patients with a class...
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| Publicado no: | Commun Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123626/ https://ncbi.nlm.nih.gov/pubmed/30271949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0077-8 |
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