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C/EBPα-dependent pre-neoplastic tumor foci are the origin of hepatocellular carcinoma and aggressive pediatric liver cancer

Recent publications show that classic hepatoblastoma (HBL) is the result of failure of hepatic stem cells to differentiate into hepatocytes; while hepatocellular carcinoma (HCC) is caused by the de-differentiation of hepatocytes into Cancer Stem Cells (CSCs). However, the mechanisms of aggressive HB...

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Detalhes bibliográficos
Publicado no:Hepatology
Principais autores: Cast, Ashley, Valanejad, Leila, Wright, Mary, Nguyen, Phuong, Gupta, Anita, Zhu, Liqin, Shin, Soona, Timchenko, Nikolai
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221081/
https://ncbi.nlm.nih.gov/pubmed/29159818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29677
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