Activation of CDK4 triggers development of Non-Alcoholic Fatty Liver Diseases

The development of Non Alcoholic Fatty Liver Disease (NAFLD) is a multiple step process. Here we show that activation of cdk4 triggers the development of NAFLD. We found that cdk4 protein levels are elevated in mouse models of NAFLD and in patients with fatty livers. This increase leads to C/EBPα ph...

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Publicado en:Cell Rep
Main Authors: Jin, Jingling, Valanejad, Leila, Nguyen, Thuy Phuong, Lewis, Kyle, Wright, Mary, Cast, Ashley, Stock, Lauren, Timchenko, Lubov, Timchenko, Nikolai A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072278/
https://ncbi.nlm.nih.gov/pubmed/27373160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.019
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