Activation of CDK4 triggers development of Non-Alcoholic Fatty Liver Diseases

The development of Non Alcoholic Fatty Liver Disease (NAFLD) is a multiple step process. Here we show that activation of cdk4 triggers the development of NAFLD. We found that cdk4 protein levels are elevated in mouse models of NAFLD and in patients with fatty livers. This increase leads to C/EBPα ph...

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Vydáno v:Cell Rep
Hlavní autoři: Jin, Jingling, Valanejad, Leila, Nguyen, Thuy Phuong, Lewis, Kyle, Wright, Mary, Cast, Ashley, Stock, Lauren, Timchenko, Lubov, Timchenko, Nikolai A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072278/
https://ncbi.nlm.nih.gov/pubmed/27373160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.019
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