CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells

The transcriptional coactivator with PDZ-binding motif (TAZ) (WWTR1) induces epithelial–mesenchymal transition and enhances drug resistance in multiple cancers. TAZ has been shown to interact with transcription factors in the nucleus, but when phosphorylated, translocates to the cytoplasm and is deg...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Nagashima, Shunta, Maruyama, Junichi, Honda, Kaori, Kondoh, Yasumitsu, Osada, Hiroyuki, Nawa, Makiko, Nakahama, Ken-ichi, Ishigami-Yuasa, Mari, Kagechika, Hiroyuki, Sugimura, Haruhiko, Iwasa, Hiroaki, Arimoto-Matsuzaki, Kyoko, Nishina, Hiroshi, Hata, Yutaka
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209642/
https://ncbi.nlm.nih.gov/pubmed/34022224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100803
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