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Validation of chemical compound library screening for transcriptional co‐activator with PDZ‐binding motif inhibitors using GFP‐fused transcriptional co‐activator with PDZ‐binding motif

Transcriptional co‐activator with PDZ‐binding motif (TAZ) plays versatile roles in cell proliferation and differentiation. It is phosphorylated by large tumor suppressor kinases, the core kinases of the tumor‐suppressive Hippo pathway. Phosphorylation induces the cytoplasmic accumulation of TAZ and...

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Bibliografische gegevens
Gepubliceerd in:Cancer Sci
Hoofdauteurs: Nagashima, Shunta, Maruyama, Junichi, Kawano, Shodai, Iwasa, Hiroaki, Nakagawa, Kentaro, Ishigami‐Yuasa, Mari, Kagechika, Hiroyuki, Nishina, Hiroshi, Hata, Yutaka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968592/
https://ncbi.nlm.nih.gov/pubmed/27009852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12936
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