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Validation of chemical compound library screening for transcriptional co‐activator with PDZ‐binding motif inhibitors using GFP‐fused transcriptional co‐activator with PDZ‐binding motif

Transcriptional co‐activator with PDZ‐binding motif (TAZ) plays versatile roles in cell proliferation and differentiation. It is phosphorylated by large tumor suppressor kinases, the core kinases of the tumor‐suppressive Hippo pathway. Phosphorylation induces the cytoplasmic accumulation of TAZ and...

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書目詳細資料
發表在:Cancer Sci
Main Authors: Nagashima, Shunta, Maruyama, Junichi, Kawano, Shodai, Iwasa, Hiroaki, Nakagawa, Kentaro, Ishigami‐Yuasa, Mari, Kagechika, Hiroyuki, Nishina, Hiroshi, Hata, Yutaka
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968592/
https://ncbi.nlm.nih.gov/pubmed/27009852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12936
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