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CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells

The transcriptional coactivator with PDZ-binding motif (TAZ) (WWTR1) induces epithelial–mesenchymal transition and enhances drug resistance in multiple cancers. TAZ has been shown to interact with transcription factors in the nucleus, but when phosphorylated, translocates to the cytoplasm and is deg...

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Foilsithe in:J Biol Chem
Main Authors: Nagashima, Shunta, Maruyama, Junichi, Honda, Kaori, Kondoh, Yasumitsu, Osada, Hiroyuki, Nawa, Makiko, Nakahama, Ken-ichi, Ishigami-Yuasa, Mari, Kagechika, Hiroyuki, Sugimura, Haruhiko, Iwasa, Hiroaki, Arimoto-Matsuzaki, Kyoko, Nishina, Hiroshi, Hata, Yutaka
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209642/
https://ncbi.nlm.nih.gov/pubmed/34022224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100803
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