CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells

The transcriptional coactivator with PDZ-binding motif (TAZ) (WWTR1) induces epithelial–mesenchymal transition and enhances drug resistance in multiple cancers. TAZ has been shown to interact with transcription factors in the nucleus, but when phosphorylated, translocates to the cytoplasm and is deg...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nagashima, Shunta, Maruyama, Junichi, Honda, Kaori, Kondoh, Yasumitsu, Osada, Hiroyuki, Nawa, Makiko, Nakahama, Ken-ichi, Ishigami-Yuasa, Mari, Kagechika, Hiroyuki, Sugimura, Haruhiko, Iwasa, Hiroaki, Arimoto-Matsuzaki, Kyoko, Nishina, Hiroshi, Hata, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209642/
https://ncbi.nlm.nih.gov/pubmed/34022224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100803
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