Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability

Doublecortin-like kinase 1 (DCLK1) is a serine/threonine-kinase with two doublecortin (DCX) domains. DCLK1 is associated with microtubules via DCX domains and regulates microtubule polymerization. DCLK1 is known to be expressed in cancer stem cells and provides cancer cells with tumor-initiating cap...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Lu, Yuxiong, Maruyama, Junichi, Kuwata, Keiko, Fukuda, Hiroyuki, Iwasa, Hiroaki, Arimoto-Matsuzaki, Kyoko, Sugimura, Haruhiko, Hata, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216093/
https://ncbi.nlm.nih.gov/pubmed/30417131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.10.014
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