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UNC119 is a binding partner of tumor suppressor Ras‐association domain family 6 and induces apoptosis and cell cycle arrest by MDM2 and p53
Ras‐association domain family 6 (RASSF6) is a tumor suppressor that interacts with MDM2 and stabilizes p53. Caenorhabditis elegans unc‐119 encodes a protein that is required for normal development of the nervous system. Humans have 2 unc‐119 homologues, UNC119 and UNC119B. We have identified UNC119...
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| Опубликовано в: : | Cancer Sci |
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| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6125449/ https://ncbi.nlm.nih.gov/pubmed/29931788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13706 |
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