Screening with a Novel Cell-Based Assay for TAZ Activators Identifies a Compound That Enhances Myogenesis in C2C12 Cells and Facilitates Muscle Repair in a Muscle Injury Model

The transcriptional coactivator with a PDZ-binding motif (TAZ) cooperates with various transcriptional factors and plays various roles. Immortalized human mammalian epithelial MCF10A cells form spheres when TAZ is overexpressed and activated. We developed a cell-based assay using sphere formation by...

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Hlavní autoři: Yang, Zeyu, Nakagawa, Kentaro, Sarkar, Aradhan, Maruyama, Junichi, Iwasa, Hiroaki, Bao, Yijun, Ishigami-Yuasa, Mari, Ito, Shigeru, Kagechika, Hiroyuki, Hata, Shoji, Nishina, Hiroshi, Abe, Shinya, Kitagawa, Masanobu, Hata, Yutaka
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993594/
https://ncbi.nlm.nih.gov/pubmed/24550007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01346-13
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