Cysteine S-Glutathionylation Promotes Stability and Activation of the Hippo Downstream Effector Transcriptional Co-activator with PDZ-binding Motif (TAZ)

Transcriptional co-activator with PDZ-binding motif (TAZ) and Yes-associated protein (YAP) are critical transcriptional co-activators downstream of the Hippo pathway involved in the regulation of organ size, tissue regeneration, proliferation, and apoptosis. Recent studies suggested common and disti...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Gandhirajan, Rajesh Kumar, Jain, Manaswita, Walla, Benedikt, Johnsen, Marc, Bartram, Malte P., Huynh Anh, Minh, Rinschen, Markus M., Benzing, Thomas, Schermer, Bernhard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882430/
https://ncbi.nlm.nih.gov/pubmed/27048650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712539
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