Inactivation of creatine kinase by S-glutathionylation of the active-site cysteine residue.

Protein S-thiolation, the formation of mixed disulphides of cysteine residues in proteins with low-molecular-mass thiols, occurs under conditions associated with oxidative stress and can lead to modification of protein function. In the present study, we examined the site of S-thiolation of the enzym...

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Bibliographic Details
Main Authors: Reddy, S, Jones, A D, Cross, C E, Wong, P S, Van Der Vliet, A
Format: Artigo
Language:Inglês
Published: 2000
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221021/
https://ncbi.nlm.nih.gov/pubmed/10769188
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