Exploring the Role of the Active Site Cysteine in Human Muscle Creatine Kinase

All known guanidino kinases contain a conserved cysteine residue that interacts with the non-nucleophilic η(1)-nitrogen of the guanidino substrate. Site-directed mutagenesis studies have shown that this cysteine is important, but not essential for activity. In human muscle creatine kinase (HMCK) thi...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wang, Pan-Fen, Flynn, Allen J., Naor, Mor M., Jensen, Jan H., Cui, Guanglei, Merz, Kenneth M., Kenyon, George L., McLeish, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556515/
https://ncbi.nlm.nih.gov/pubmed/16981706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0607002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky