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Mutation of conserved active-site threonine residues in creatine kinase affects autophosphorylation and enzyme kinetics.

Muscle-type creatine kinase (MM-CK) is a member of an isoenzyme family with key functions in cellular energetics. It has become a matter of debate whether the enzyme is autophosphorylated, as reported earlier [Hemmer, Furter-Graves, Frank, Wallimann and Furter (1995) Biochim. Biophys. Acta 1251, 81-...

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Detalhes bibliográficos
Main Authors: Stolz, Martin, Hornemann, Thorsten, Schlattner, Uwe, Wallimann, Theo
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222532/
https://ncbi.nlm.nih.gov/pubmed/11964180
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