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Effect of Hemopexin Treatment on Outcome after Intracerebral Hemorrhage in Mice

Heme release from hemoglobin may contribute to secondary injury after intracerebral hemorrhage (ICH). The primary endogenous defense against heme toxicity is hemopexin, a 57 kDa glycoprotein that is depleted in the CNS after hemorrhagic stroke. We hypothesized that systemic administration of exogeno...

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Bibliografske podrobnosti
izdano v:Brain Res
Main Authors: Chen-Roetling, Jing, Li, Yang, Cao, Yang, Yan, Zhe, Lu, Xiangping, Regan, Raymond F.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206022/
https://ncbi.nlm.nih.gov/pubmed/33930375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2021.147507
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