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Effect of Hemopexin Treatment on Outcome after Intracerebral Hemorrhage in Mice

Heme release from hemoglobin may contribute to secondary injury after intracerebral hemorrhage (ICH). The primary endogenous defense against heme toxicity is hemopexin, a 57 kDa glycoprotein that is depleted in the CNS after hemorrhagic stroke. We hypothesized that systemic administration of exogeno...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Brain Res
Hauptverfasser: Chen-Roetling, Jing, Li, Yang, Cao, Yang, Yan, Zhe, Lu, Xiangping, Regan, Raymond F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206022/
https://ncbi.nlm.nih.gov/pubmed/33930375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2021.147507
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