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Astrocyte Overexpression of Heme Oxygenase-1 Improves Outcome after Intracerebral Hemorrhage

BACKGROUND AND PURPOSE: Heme oxygenase-1 (HO-1) catalyzes the rate-limiting reaction of heme breakdown, and may have both antioxidant and pro-oxidant effects. In prior studies, HO-1 overexpression protected astrocytes from heme-mediated injury in vitro. In the present study, we tested the hypothesis...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stroke
Prif Awduron: Chen-Roetling, Jing, Song, Wei, Schipper, Hyman M., Regan, Christopher S., Regan, Raymond F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373967/
https://ncbi.nlm.nih.gov/pubmed/25690543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.008686
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