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Astrocyte Overexpression of Heme Oxygenase-1 Improves Outcome after Intracerebral Hemorrhage
BACKGROUND AND PURPOSE: Heme oxygenase-1 (HO-1) catalyzes the rate-limiting reaction of heme breakdown, and may have both antioxidant and pro-oxidant effects. In prior studies, HO-1 overexpression protected astrocytes from heme-mediated injury in vitro. In the present study, we tested the hypothesis...
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| Publicado en: | Stroke |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4373967/ https://ncbi.nlm.nih.gov/pubmed/25690543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.008686 |
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