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Systemic Hemin Therapy Attenuates Blood-Brain Barrier Disruption after Intracerebral Hemorrhage

Injury to the blood-brain barrier (BBB) is a key feature of intracerebral hemorrhage (ICH) and may contribute to perihematomal cell injury. Pretreatment with the heme oxygenase (HO)-1 inducer hemin improves barrier function and neurological outcome in experimental models of traumatic and ischemic CN...

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Détails bibliographiques
Publié dans:Neurobiol Dis
Auteurs principaux: Lu, Xiangping, Chen-Roetling, Jing, Regan, Raymond F.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221186/
https://ncbi.nlm.nih.gov/pubmed/24952361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.06.005
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